Skip to content
View hh-health-AI's full-sized avatar
🎯
Focusing
🎯
Focusing

Block or report hh-health-AI

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Content in all repositories owned by your account will be closed.
Maximum 250 characters. Please don’t include any personal information such as legal names or email addresses. Markdown is supported. This note will only be visible to you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
hh-health-AI/README.md

HH Health AI — healthcare investing, biomedical evidence and AI. Evidence to assumptions to valuation to human judgment.

Try a demo   ·   Read a research case   ·   Review the evaluation

Better evidence. Explicit assumptions. Falsifiable investment views.
AI should make research more inspectable—not make judgment less accountable.

About me

I build open-source tools for healthcare investing, biotech research and AI-assisted fundamental analysis. My work connects biomedical evidence and public datasets to the questions that matter for an investment thesis: what changes, how it changes the model, and what would prove the thesis wrong.

  • Research: Biotech, pharmaceuticals, medtech, life sciences tools and healthcare services.
  • Evidence: Clinical trials, regulatory catalysts, utilization, reimbursement, provider economics and company filings.
  • Methods: DCF, risk-adjusted NPV, scenarios, catalyst analysis and evidence-to-valuation workflows.

Start here: Healthcare Equity Research Platform

The flagship integration point for healthcare equity research.

A synthesis layer and 12 modular evidence pipelines connect clinical and regulatory developments, patient populations, commercial adoption, reimbursement, financial disclosures and valuation.

Core value: Turn a source-backed observation into an explicit model assumption and a testable investment view.

Clinical evidence → Probability & demand → Commercial assumptions → DCF / rNPV → Investment thesis

Explore the modules →

The platform combines 12 evidence modules, nine biomedical workflows, and an investment synthesis layer. Python utilities retrieve data, compare structured records and calculate scenarios; host-loaded skills guide reading and interpretation. The standalone repositories remain authoritative for their specialist scripts; bundled modules are versioned snapshots.

Inspect the research

Case Decision question Reproducible output
Biotech: HELIOS-B / vutrisiran How does clinical evidence differ from a completed approval decision? Approval-gate and commercial rNPV sensitivities.
Medtech: Intuitive Surgical How do procedure growth and recurring economics affect revenue? Platform-specific drivers and revenue sensitivities.
Managed care: medical costs What does a medical-cost-ratio change imply for earnings? Reconciled premiums and static earnings/EPS sensitivities.

These are dated research demonstrations using real primary-source facts and explicit modeling assumptions. They are not current stock recommendations or fully underwritten price targets.

Source-backed semantic development set · Case verification ledger · Choose an installation path

Research workflow

flowchart TD
    Q["Research question"] --> E["Primary evidence and source ledger"]
    E --> A["Assumptions and uncertainty"]
    A --> M["Models and sensitivities"]
    E --> C["Source and accuracy checks"]
    C --> M
    M --> T["Thesis, catalyst and falsifier"]
    T --> R["Monitor and re-underwrite"]
    R --> E
Loading

Detailed source workflow · Maintenance and synchronization

Selected research projects

From trial results to underwriting assumptions.

Organize trial readouts and regulatory events around approval probability, label, timing and clinical differentiation.

Clinical trials FDA catalysts

Integrated module →

Understand the economics of market access.

Connect coverage and payment evidence to access, pricing assumptions and healthcare business economics.

Coverage Payment Market access

Integrated module →

Test demand against observable evidence.

Use prescribing, utilization and launch proxies to challenge commercial assumptions and revenue trajectories.

Utilization Launch tracking

Integrated module →

Bring financial discipline to the healthcare thesis.

Examine company filings, accounting signals and insider activity alongside the scientific and commercial evidence.

SEC EDGAR Financial forensics

Integrated module →

Explore all 12 evidence modules
Research layer Integrated module
Clinical and regulatory clinical-catalysts
Publications, guidelines and expert signals evidence-catalysts
Safety signals fda-safety-signals
Prescription utilization rx-utilization
Epidemiology and patient populations epi-demand
Coverage and reimbursement cms-reimbursement
Provider adoption provider-adoption
Provider economics provider-economics
Procedure and coding exposure procedure-exposure
Patents, exclusivity and loss of exclusivity ip-exclusivity
International access global-access
Company filings and accounting sec-forensics

Tools and research craft

Python for public-data tooling; Markdown for agent instructions; Git for versioned research; GitHub for open collaboration.

Domain expertise: Biotech · Pharma · Medtech · Life Sciences Tools · Managed Care · Healthcare Services · Digital Health

Research methods: DCF · rNPV · Scenario Analysis · Catalyst Research · Evidence Synthesis

Research principles

Primary sources first. Important numbers should retain their source, vintage and limitations.

Evidence is not the conclusion. Observations, assumptions, calculations and investment judgment should remain distinguishable.

Models must be challengeable. A thesis needs explicit sensitivities, disconfirming evidence and a clear account of what would change the view.

Human judgment stays in the loop. These AI agents, skills and research workflows are designed to support institutional-quality due diligence—not to replace analyst accountability or imply independent certification.

Responsible use of AI

AI supports research and education; outputs require source verification and accountable human review. Protect patient information, disclose material AI assistance and retain uncertainty. These tools are not validated for patient care or autonomous investment decisions.

Read the responsible AI policy — practical standards for evidence, disclosure, privacy, human oversight and corrections.

Connect

Working on healthcare investing, biomedical data or AI-enabled research? Project issues and pull requests are welcome.

Contribute a case, adapter or reproducible failure


Research and educational tools—not medical advice or investment recommendations.
Public project capabilities vary; inspect each repository's documentation and limitations.

Pinned Loading

  1. healthcare-equity healthcare-equity Public

    Synthesis engine for buy-side healthcare equity research.

    Python 93 7

  2. clinical-catalysts clinical-catalysts Public

    Science, trials, and FDA evidence engine for buy-side healthcare equity research. Answers: does the science work, will FDA/EMA allow it, when is the binary event, and who else is coming.

    Shell 1

  3. cms-reimbursement cms-reimbursement Public

    Access-and-payment evidence engine for buy-side healthcare equity research.

    Shell 1

  4. epi-demand epi-demand Public

    Epidemiology and end-market demand.

    Python 1

  5. evidence-catalysts evidence-catalysts Public

    Guidelines, conferences and literature velocity.

    Python 1

  6. global-access global-access Public

    International HTA, pricing and approvals.

    Python 1